Wednesday, March 2, 2011

Acetylcholinesterase Inhibitors and Friend.



Aricept(donepezil)-Prevents the breakdown of acetylcholine in the brain. Mild Side Effects: Nausea, vomiting. 80% see improved cognitve functioning for up to two years.

Razadynde(galantamine)- Cholinesterase inhibitor that also can stimulate nicotonic receptors in the brain that can spur the release of more acetylcholine. Side Effects include potentially harmful effect on liver and kidneys.

Exelon(rivastigmine)-Similar to Aricept. Only 25-30% of Recipients see cognitve improvements but the drug has shown zero liver toxicity.

Namenda(memantine) Antagonist that blocks the toxic effects associated with excess glutamate and regulates glutamate activation. Side Effects include dizziness, headache, and confusion. Often prescribed with Aricept for Moderate to Severe stages.

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